Publications
2024
56.Kaixuan Zhang, Mingxin Zhao,* Jiaxu Guo, Yu-Xin Luan*, & Pingping Tang* Photoredox Amidotrifluoromethoxylation of Styrenes with Bifunctional N-OCF3 Reagent via Electron Donor-Acceptor Complex Activation, CCS Chem. 2024, e202506759. DOI: 10.31635/ccschem.025.202506759
55.Wanqiu Zhao , Aijia Zhang , Qingyun Huang*, Pingping Tang*, Selective meta-C-H trifluoromethylation of pyridines via 1,4-dihydropyridine phosph-onate, Chinese Chemical Letters (2025), DOI:10.1016/j.cclet.2025.112133
54.Jingya Zhou, Longhui Chen, Ziang Miao, Jinjin Li, Yu-xin Luan*, Li Chen* and Pingping Tang*, Photocatalyst-Regulated Trifluoromethoxylation of Aryl Halides under Silver Promotion, J.Am.Chem.Soc.2025,147,38979−38986, DOI: 10.1021/jacs.5c11167
53.Lu Guo, Ruijian Fang, Yun Liu, Zhenbo Zhao, Nuochen Ye, Zhijie Deng, Muhammad Bilal Altaf and Pingping Tang*, Silver-mediated intermolecular ortho-trifluoromethoxylation of pyridyl-arenes, Org. Biomol. Chem. 2025, 23, 9336, DOI: 10.1039/d5ob01162k
52.Pengfei Yang, Sihan Chen, Yu-Xin Luan* and Pingping Tang*, Divergent Mono- and Di-trifluoromethylthiolation of Bicyclo[1.1.0]butane and Bicyclo[2.1.0]pentane. Chin. J. Chem. 2025, 43, 2917—2921. DOI: 10.1002/cjoc.70194
51.Pengfei Yang, Sihan Chen, Jiaxin Lu, Pengfei Ning, Wanqiu Zhao, Yu-Xin Luan, Li Chen,* Xiufang Xu,* and Pingping Tang*,Silver-Catalyzed syn-Stereoselective Trifluoromethoxylation of Bicyclo[1.1.0]butanes, Org. Lett. 2025, 27, 7679−7684, DOI: 10.1021/acs.orglett.5c02396
50.Mingxin Zhao, Ziyang Zhou and Pingping Tang *, Synthesis of α-trifluoromethoxy-sulfide through the Pummerer rearrangement. Org. Biomol. Chem. 2025, 23, 6127. DOI: 10.1039/d5ob00673b
49.Lu Guo, Kaiyang Bi, Tengying Chen, Jie-Lun Yan, Haowen Tian, Mingxin Zhao, Qingyun Huang,* and Pingping Tang*, Stereoselective Synthesis of the Core Ring System of Lancifonins A−D, Org. Lett. 2025, 27, 3123−3127, DOI:10.1021/acs.orglett.5c00263
48.Yafeng Si, Yuntao Liu, Fan Zhou, Lei Fang, Kang Wu, Yu-Xin Luan,* Li Chen,and Pingping Tang*,Cobalt-Catalyzed Enantioselective Hydrotrifluoromethoxylation of Aromatic Alkenes, Angew. Chem. Int. Ed. 2025, 64, e202501680, DOI: 10.1002/anie.202501680
47.Rui Liu, Yangdong Hou *, and Pingping Tang*, Bromotrifluoromethoxylation of allenes: expedient access to allylic trifluoromethoxy derivatives, Org. Chem. Front. 2025, 12, 3960. DOI:10.1039/d4qo02426e
46.Lingduan Meng, Jingjing Liu, Zeying Sun, Yangdong Hou,* Qingyun Huang* and Pingping Tang*, Forging the tricyclic core framework of euphordraculoate B via a Barbier-type allyl addition, Org. Biomol. Chem.2025, 23, 589, DOI: 10.1039/d4ob01743a
45.Muhammad Bilal Altaf, Yu-Xin Luan* & Pingping Tang*. Recent advances in silver-mediated/catalyzed synthesis of trifluoromethoxy compounds. Sci China Chem, 2025, 68: 1717–1730, DOI: 10.1007/s11426-024-2342-4
44.Yangdong Hou*, Yicheng Luo, Pingping Tang*.Rhodium-Catalyzed Trifluoromethoxylation of Allenylic Trichloroacetimidates. Org. Lett. 2024, 26, 9764−9768.DOI: 10.1021/acs.orglett.4c03676
43. Liyan Wang, Yafeng Si, Yuxin Luan*, Pingping Tang*. Rhodium-Catalyzed Asymmetric Trifluoromethoxylation of Racemic Allylic Trichloroacetimidates. CCS Chem. 2024. DOI: 10.31635/ccschem.024.202404011.
42. Zhijie Deng, Lingduan Meng, Xiao Bing, Shaoxiong Niu, Xiaofeng Zhang, Junqin Peng, Yuxin Luan, Li Chen*, Pingping Tang*. Silver-Enabled Dearomative Trifluoromethoxylation of Indoles. J. Am. Chem. Soc. 2024, 146, 2325−2332. DOI: 10.1021/jacs.3c11653.
2023
38. Mingxin Zhao, Miao Chen, Tian Wang, Qian Peng*, Pingping Tang*. Fluorocarbonylation via Palladium/phospgine synergistic catalysis. Nat. Commun. 2023, 14, 4583. DOI: 10.1038/s41467-023-40180-6.
40. Yafeng Si, Pingping Tang*. Development and Application of Trifluoromethoxylating Reagent. Chin. J. Chem. 2023, 41, 2179−2196. DOI: 10.1002/cjoc.202300093.
39. Yangdong Hou, Zhang Zhang, Xinyu Sun, Zheng Yang, Yuxin Luan* Pingping Tang*. Copper-Catalyzed Enantioselective Trifluoromethoxylation of Propargyl Sulfonates. Angew. Chem. Int. Ed. 2023, 62, e202218919. DOI:10.1002/anie.202218919.
2022
38. Jingrui Xin, Tengying Chen, Pingping Tang*. Direct Trifluoromethylthiolation of Aziridines: Cation-Controlled Diverse Synthesis of Trifluoromethylthiolated Isothiocyanates and Amines. Org. Lett. 2022, 24, 2035−2039. DOI:10.1021/acs.orglett.2c00558.
37. Jingrui Xin, Xiangyu Deng, Pingping Tang*. Silver-Catalyzed Triflfluoromethoxylation of Aziridines. Org. Lett. 2022, 24, 881−885. DOI:10.1021/acs.orglett.1c04226.
36. Zhijie Deng, Pingping Tang*. Design and Reaction of Nucleophilic and Radical Heptafluoroisopropoxylation Reagents. Chin. J. Org. Chem. 2022, 42, 305-306. DOI:10.6023/cjoc202200002.
35. FengLing Qing*, XinYuan Liu*, JunAn Ma*, Qilong Shen*, Qiuling Song*, Pingping Tang*. A Fruitful Decade of Organofluorine Chemistry: New Reagents and Reactions. CCS Chem. 2022, 4, 2518–2549. DOI: 10.31635/ccschem.022.202201935.
2021
34. Lu Guo, Pingping Tang*. Recent Advance in the Synthesis of Natural Products of Schisandra Triterpenoid. Chin. J. Org. Chem. 2021, 41, 3816～3825. DOI: 10.6023/cjoc202105049.
33. Xiaohuan Jiang, Pingping Tang*. Diverse Synthesis of Chiral Trifluoromethylated Alkanes via Nickel-Catalyzed Asymmetric Reductive Cross-Coupling Fluoroalkylation. Chin. J. Org. Chem. 2021, 41, 2525～2527. DOI: 10.6023/cjoc202100045.
32. Feng Wang, Yuecong Guo, Yutong Zhang, Pingping Tang*. Silver-Catalyzed Dibromotrifluoromethoxylation of Terminal Alkynes. ACS Catal. 2021, 11, 3218−3223. DOI: 10.1021/acscatal.1c00090.
31. Xiaohuan Jiang, Pingping Tang*. Recent Advances of Trifluoromethoxylation Reactions Using TFMS and TFBO. Chin. J. Chem. 2021, 39, 255—264. DOI: 10.1002/cjoc.202000465.
2020
30. Feng Wang, Pingping Tang*. Recent Advances in Trifluoromethoxylation Reactions. Chin. J. Org. Chem. 2020, 40, 1805～1813. DOI:10.6023/cjoc202003048.
29. Xiaohuan Jiang, Pingping Tang*. Silver-Catalyzed Trifluoromethoxylation of Alkyl Trifluoroborates. Org. Lett. 2020, 22, 5135−5139. DOI:10.1021/acs.orglett.0c01741.
28. Zhijie Deng, Mingxin Zhao, Feng Wang, Pingping Tang*. Selective C-H triflfluoromethoxylation of (hetero) arenes as limiting reagent. Nat. Commun. 2020, 11, 2569. DOI:10.1038/s41467-020-16451-x.
27. Yan Li, Yang Yang, Jinrui Xin, Pingping Tang*. Nucleophilic trifluoromethoxylation of alkyl halides without silver. Nat. Commun. 2020, 11, 755. DOI: 10.1038/s41467-020-14598-1.
26. Qingyun Huang, Pingping Tang*. Silver-Mediated Intermolecular Iodotrifluoromethoxylation of Alkenes. J. Org. Chem. 2020, 85, 2512−2519. DOI: 10.1021/acs.joc.9b03206.
25. Xiaohuan Jiang, Pingping Tang*. Advances in Enantioselective Construction of Trifluoromethoxylated Stereogenic Carbon Centers. Chin. J. Chem. 2020, 38, 101—102. DOI: 10.1002/cjoc.201900374.
24. Qiang Li, Jialiang Chen, Marko Trajkovski, Yifei Zhou, Chaochao Fan, Kuan Lu, Pingping Tang, Xuncheng Su, Janez Plavec*, Zhen Xi, Chuanzheng Zhou*. 4′-Fluorinated RNA: Synthesis, Structure, and Applications as a Sensitive 19F NMR Probe of RNA Structure and Function. J. Am. Chem. Soc. 2020, 142, 4739−4748. DOI: 10.1021/jacs.9b13207.
23. Qingbing Wang, Juan Duan, Pingping Tang, Gong Chen*, Gang He*. Synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-dihydropyridines. Sci. China. Chem. 2020, 63, 1613–1618. DOI: 10.1007/s11426-020-9813-5.
2019
22. Shaoqiang Yang, Miao Chen, Pingping Tang*. Visible-Light Photoredox-Catalyzed and Copper-Promoted Trifluoromethoxylation of Arenediazonium Tetrafluoroborates. Angew. Chem. Int. Ed. 2019, 58, 7840–7844. DOI: 10.1002/anie.201901447.
21. Xiaofei Zhang, Pingping Tang*. Recent advances in new trifluoromethoxylation reagents. Sci. China. Chem. 2019, 62, 525–532. DOI: 10.1007/s11426-018-9402-x.
20.Hengtao Wang, Liang Wang, Yihang Li, Xiunan Zhang, Pingping Tang*. Collective Synthesis of Schilancidilactones A, B and Schilancitrilactones A, B, C, 20-epi-Schilancitrilactone A. Chin. J. Chem. 2019, 37, 255—268. DOI:10.1002/cjoc.201800557.
2018
19. Feng Wang, Peng Xu, Fei Cong, Pingping Tang*. Silver-mediated oxidative functionalization of alkylsilanes. Chem. Sci. 2018, 9, 8836. DOI: 10.1039/c8sc03730b.
18. Jie Liu, Yongliang Wei, Pingping Tang*. Cobalt-Catalyzed Trifluoromethoxylation of Epoxides. J. Am. Chem. Soc. 2018, 140, 15194−15199. DOI:10.1021/jacs.8b10298.
17. Haodong Yang, Feng Wang, Xiaohuan Jiang, Yu Zhou, Xiufang Xu*, Pingping Tang*. Silver-Promoted Oxidative Benzylic C−H Trifluoromethoxylation. Angew. Chem. Int. Ed. 2018, 57, 13266–13270. DOI: 10.1002/anie.201807144.
16. Fei Cong, Yongliang Wei, Pingping Tang*. Combining photoredox and silver catalysis for azidotrifluoromethoxylation of styrenes. Chem. Commun. 2018, 54, 4473. DOI: 10.1039/c8cc01096j.
15. Xiaohuan Jiang, Zhijie Deng, Pingping Tang*. Direct Dehydroxytrifluoromethoxylation of Alcohols. Angew. Chem. Int. Ed. 2018, 57, 292–295. DOI:10.1002/anie.201711050.
2017
14. Hengtao Wang, Xiunan Zhang, Pingping Tang*. Total syntheses of schilancidilactones A and B, schilancitrilactone A, and 20-epi-schilancitrilactone A via late-stage nickel-catalyzed cross coupling. Chem. Sci. 2017, 8, 7246. DOI: 10.1039/c7sc03293e.
13. Liyan Wang, Xiaohuan Jiang, Pingping Tang*. Silver-mediated fluorination of alkyl iodides with TMSCF3 as the fluorinating agent. Org. Chem. Front. 2017, 4, 1958. DOI: 10.1039/c7qo00450h.
12.Shuo Guo, Fei Cong, Rui Guo, Liang Wang, Pingping Tang*. Asymmetric silver-catalysed intermolecular bromotrifluoromethoxylation of alkenes with a new trifluoromethoxylation reagent. Nature. Chem. 2017, 9, 546–551. DOI: 10.1038/NCHEM.2711.
11. Yan Li,Xiaohuan Jiang,Chaoyue Zhao,Xiaoning Fu,Xiufang Xu*,Pingping Tang*. Silver-Catalyzed Anti-Markovnikov Hydroxyfluorination of Styrenes. ACS Catal. 2017, 7, 3, 1606–1609. DOI: 10.1021/acscatal.6b03529.
10. Peng Xu, Feng Wang, Guilan Fan, Xiufang Xu*, Pingping Tang*. Hypervalent Iodine(III)-Mediated Oxidative Fluorination of Alkylsilanes by Fluoride Ions. Angew. Chem. Int. Ed. 2017, 56, 1101–1104. DOI: 10.1002/anie.201609741.
9. Gengyang Yuan, Feng Wang, Nickeisha A. Stephenson, Lu Wang, Benjamin H. Rotstein, Neil Vasdev, Pingping Tang, Steven H. Liang*. Metal-free 18F-labeling of aryl-CF2H via nucleophilic radiofluorination and oxidative C-H activation. Chem. Commun. 2017, 53, 126. DOI: 10.1039/c6cc07913j.
2016
8. Rui Guo, Zhengjuan Zhang, Feng Shi, Pingping Tang*. Tunable Cascade Reaction of Aryl Diazonium Salts and Trialkylamine: Synthesis of Monofluorinated Arylhydrazones and gem-Difluorinated Azo Compounds. Org. Lett. 2016, 18, 1008−1011. DOI: 10.1021/acs.orglett.6b00130.
2015
7. Xiaofei Zhang, Haodong Yang, Pingping Tang*. Transition-Metal-Free Oxidative Aliphatic C–H Azidation. Org. Lett. 2015, 17, 5828−5831. DOI: 10.1021/acs.orglett.5b03001.
6. Liang Wang, Hengtao Wang, Yihang Li, Pingping Tang*. Total Synthesis of Schilancitrilactones B and C. Angew. Chem. Int. Ed. 2015, 54, 5732–5735. DOI: 10.1002/anie.201501169.
5. Shuo Guo, Xiaofei Zhang, Pingping Tang*. Silver-Mediated Oxidative Aliphatic C-H Trifluoromethylthiolation. Angew. Chem. Int. Ed. 2015, 54, 4065–4069. DOI: 10.1002/anie.201411807.
4. Xiaofei Zhang, Shuo Guo, Pingping Tang*. Transition-metal free oxidative aliphatic C–H fluorination. Org. Chem. Front. 2015, 2, 806–810. DOI: 10.1039/c5qo00095e.
3. Rui Guo, Haodong Yang, Pingping Tang*. Silver-catalyzed Meerwein arylation: intermolecular and intramolecular fluoroarylation of styrenes. Chem. Commun. 2015, 51, 8829. DOI: 10.1039/c5cc02446c.
2. Peng Xu, Shuo Guo, Liyan Wang, Pingping Tang*. Silver-Catalyzed Oxidative Activation of Benzylic C-H Bonds for the Synthesis of Difluoromethylated Arenes.Angew. Chem. Int. Ed. 2014, 53, 5955–5958. DOI: 10.1002/anie.201400225.
